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Title:
【発明の名称】プロペンカルボン酸アミドキシム誘導体、その製法、及びこの誘導体を含有する医薬組成物
Document Type and Number:
Japanese Patent JP2003528073
Kind Code:
A
Abstract:
The invention refers to novel propenecarboxylic acid amidoxime derivatives furthermore N-oxides and/or geometrical isomers and/or optical isomers and/or pharmaceutically suitable acid addition salts and/or quaternary derivatives thereof. The novel compounds are suitable for the treatment of a state connected with oxygen deficit and/or energy deficit, or a disease based on PARP inhibition, especially an autoimmune or neurodegenerative disease, and/or a viral disease, and/or a disease caused by a toxic effect.

Inventors:
Peter Literat Nadi
Barrage Shigegi
Karman takatu
Application Number:
JP2001568886A
Publication Date:
September 24, 2003
Filing Date:
March 13, 2001
Export Citation:
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Assignee:
N Gene Research Laboratories, Inc.
International Classes:
A61K31/155; A61K31/16; A61K31/40; A61K31/41; A61K31/4245; A61K31/4453; A61K31/454; A61K31/4725; A61K31/495; A61K31/496; A61K31/535; A61K31/5375; A61K31/5377; A61K31/5395; A61K31/55; A61P1/04; A61P1/16; A61P3/04; A61P3/10; A61P7/02; A61P9/00; A61P9/02; A61P9/10; A61P9/12; A61P17/00; A61P17/02; A61P17/06; A61P19/02; A61P21/04; A61P25/00; A61P25/02; A61P25/16; A61P25/28; A61P29/00; A61P31/04; A61P31/14; A61P31/18; A61P37/02; A61P43/00; C07C249/06; C07C251/40; C07D295/12; C07D207/325; C07D271/06; C07D271/07; C07D273/02; C07D273/04; C07D295/13; C07D413/06; (IPC1-7): C07C251/40; A61K31/155; A61K31/4245; A61K31/4453; A61K31/454; A61K31/4725; A61K31/495; A61K31/496; A61K31/5375; A61K31/5377; A61K31/5395; A61K31/55; A61P1/04; A61P1/16; A61P3/04; A61P3/10; A61P7/02; A61P9/00; A61P9/02; A61P9/10; A61P9/12; A61P17/00; A61P17/02; A61P17/06; A61P19/02; A61P21/04; A61P25/00; A61P25/02; A61P25/16; A61P25/28; A61P29/00; A61P31/04; A61P31/14; A61P31/18; A61P37/02; A61P43/00; C07C249/06; C07D271/06; C07D273/04; C07D295/12; C07D413/06
Domestic Patent References:
JP2001511776A2001-08-14
JP2002534523A2002-10-15
JP2002544199A2002-12-24
JP2003502286A2003-01-21
JP2003508400A2003-03-04
JP2001511776A2001-08-14
JP2002534523A2002-10-15
JP2002544199A2002-12-24
JP2003502286A2003-01-21
JP2003508400A2003-03-04
Attorney, Agent or Firm:
Shoichi Takezawa (1 person outside)