Title:
【発明の名称】システインプロテアーゼの可逆的インヒビターとして有益な新規スピロ複素環化合物
Document Type and Number:
Japanese Patent JP2003529546
Kind Code:
A
Abstract:
Disclosed are novel cathepsin S, K, F, L and B reversible inhibitory compounds of formulas (I), (II), (Ia) and (Ib) further defined herein. The compounds are useful for treating autoimmune diseases. Also disclosed are processes for making such novel compounds.
Inventors:
Emmanuel Michael Jay
Fly Lee L
Hicky Eugene Earl
Liu Weimin
Marwick Tina M
Spero Dennis M
Sansan Shin
Thomson David S
Ward Yancey Dee
Young Eric Earl Earl
Fly Lee L
Hicky Eugene Earl
Liu Weimin
Marwick Tina M
Spero Dennis M
Sansan Shin
Thomson David S
Ward Yancey Dee
Young Eric Earl Earl
Application Number:
JP2001523393A
Publication Date:
October 07, 2003
Filing Date:
August 28, 2000
Export Citation:
Assignee:
Boehringer Ingelheim Pharmaceuticals, Inc.
International Classes:
A61K31/428; A61K31/4468; A61K31/4535; A61K31/454; A61K31/496; A61K31/4965; A61K31/506; A61K31/536; A61K31/5375; A61P1/04; A61P3/10; A61P5/14; A61P9/10; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P19/08; A61P19/10; A61P21/04; A61P25/00; A61P25/02; A61P25/28; A61P29/00; A61P37/00; A61P37/02; A61P37/08; C07D205/04; C07D207/14; C07D207/16; C07D211/58; C07D211/66; C07D309/14; C07D335/02; C07D401/04; C07D401/12; C07D403/06; C07D409/12; C07D413/12; C07D417/12; C07D451/04; (IPC1-7): C07D205/04; A61K31/428; A61K31/4468; A61K31/454; A61K31/496; A61K31/4965; A61K31/506; A61K31/536; A61K31/5375; A61P1/04; A61P3/10; A61P5/14; A61P9/10; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P19/08; A61P21/04; A61P25/00; A61P25/02; A61P25/28; A61P29/00; A61P37/02; A61P37/08; C07D207/16; C07D211/66; C07D309/14; C07D335/02; C07D401/12; C07D403/06; C07D409/12; C07D413/12; C07D417/12; C07D451/04
Domestic Patent References:
| JP2002539192A | 2002-11-19 |
Attorney, Agent or Firm:
Minoru Nakamura (9 outside)