Title:
【発明の名称】ヒドロキシマタイレジノールの投与によるベータ-カテニンの細胞内レベルの減少
Document Type and Number:
Japanese Patent JP2003530436
Kind Code:
A
Abstract:
The present invention relates to a method for decreasing the intracellular, especially nuclear level of beta-catenin in an individual and to a method for the prevention or treatment of a disease or condition in an individual, wherein said disease or condition is related to a mutant APC gene or to an elevated level of intracellular beta-catenin. Furthermore, the invention relates to methods for screening a subject to determine if said subject is a carrier of a mutant APC gene, and to methods for diagnosing an individual's predisposition for a disease or condition in an individual, said disease or condition being related to a mutant APC gene or to an elevated level of intracellular beta-catenin.
Inventors:
Mutanen, Maruya
Application Number:
JP2001576020A
Publication Date:
October 14, 2003
Filing Date:
February 08, 2001
Export Citation:
Assignee:
Hormos Nutraceutical Osamu Yukiture Limited
International Classes:
C07D307/33; A61K31/365; A61P1/00; A61P35/00; A61P43/00; (IPC1-7): A61K31/365; A61P1/00; A61P35/00; A61P43/00; C07D307/33
Attorney, Agent or Firm:
Sota Asahina (3 outside)