Title:
【発明の名称】細胞、神経系-特異的抗原およびそれらの用途
Document Type and Number:
Japanese Patent JP2003532618
Kind Code:
A
Abstract:
Compositions and methods are provided for treating injury to or disease of the central or peripheral nervous system. In one embodiment, treatment is effected using activated T cells that recognize an antigen of the nervous system or a peptide derived therefrom or a derivative thereof to promote nerve regeneration or to prevent or inhibit neuronal degeneration within the nervous system. Treatment involves administering an NS-specific antigen or peptide derived therefrom or a derivative thereof, or a nucleotide sequence encoding said antigen or peptide, to promote nerve regeneration or to prevent or inhibit neuronal degeneration in the nervous system, either the central nervous system or the peripheral nervous system. The NS-specific activated T cells can be administered alone or in combination with NS-specific antigen or peptide derived therefrom or a derivative thereof or a nucleotide sequence encoding said antigen or peptide, or any combination thereof.
Inventors:
Eisenbach-Schwartz, Michael
Cohen, Irun Earl.
Beselman, Pierre
Mosonego, Aaron
Moalem, zira
Cohen, Irun Earl.
Beselman, Pierre
Mosonego, Aaron
Moalem, zira
Application Number:
JP2000549639A
Publication Date:
November 05, 2003
Filing Date:
May 19, 1999
Export Citation:
Assignee:
Yeda Research and Development Company Limited
International Classes:
C12N15/09; A61K31/711; A61K35/26; A61K38/00; A61K38/17; A61K39/00; A61P25/28; C07K14/47; C07K14/705; A61K48/00; (IPC1-7): A61K38/00; A61K31/711; A61K35/26; A61K39/00; A61P25/28
Attorney, Agent or Firm:
Funakashi Eiko