Title:
【発明の名称】潜在的な免疫優性アセチルコリン受容体アルファ・サブユニット・ペプチドの同定
Document Type and Number:
Japanese Patent JP2003533443
Kind Code:
A
Abstract:
The present invention is directed to the treatment of autoimmune diseases, in particular of Myasthenia Gravis. This invention provides novel autoimmune dominant peptides derived from the acetylcholine receptor, as well as methods for preparing the peptides. The present invention further provides complexes comprising these peptides associated with an appropriate major histocompatibility complex (MHC) molecule and methods for making these complexes. The complexes of the present invention can be used therapeutically or prophylactically for treating Myasthenia Gravis.
Inventors:
Deshpande, Shrikant
Edward Spack
Weaner, Nancy
Arimiri, Subhashini
Edward Spack
Weaner, Nancy
Arimiri, Subhashini
Application Number:
JP2001572537A
Publication Date:
November 11, 2003
Filing Date:
March 30, 2001
Export Citation:
Assignee:
Corixa Corporation
International Classes:
A61K39/00; A61P21/04; A61P37/00; A61P37/06; C07K7/08; C07K14/705; C07K14/74; A61K38/00; C07K19/00; (IPC1-7): A61K38/00; A61K39/00; A61P21/04; A61P37/06; C07K7/08; C07K14/74; C07K19/00
Attorney, Agent or Firm:
Takashi Ishida (4 others)