Title:
チエノピロリジノン
Document Type and Number:
Japanese Patent JP2004502694
Kind Code:
A
Abstract:
The invention is directed to substituted thieno[2,3-b]pyrrolidin-5-ones. The compounds are useful as inhibitors of cellular production of tumor necrosis factor (TNF-alpha) and as antiproliferative agents. These compounds are useful in the treatment or control of neuro-degenerative diseases, cardiovascular diseases, cancer or inflammatory diseases.
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Inventors:
Gil, Adrian Liam
Harris, William
Harris, William
Application Number:
JP2002507819A
Publication Date:
January 29, 2004
Filing Date:
June 28, 2001
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
A61K31/407; A61K31/4155; A61K31/4178; A61K31/4184; A61P9/00; A61P25/28; A61P29/00; A61P35/00; C07D233/54; C07D495/04; (IPC1-7): C07D495/04; A61K31/407; A61K31/4155; A61K31/4178; A61K31/4184; A61P9/00; A61P25/28; A61P29/00; A61P35/00
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda
Fumio Shinoda