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Title:
抗結核剤の新規な医薬組成物及びその調製方法
Document Type and Number:
Japanese Patent JP2004505918
Kind Code:
A
Abstract:
A pharmaceutical composition of anti-tubercular drugs for oral use comprising Rifampicin and/or Isoniazid wherein the bioavailability of Rifampicin and/or other drugs is enhanced. Preferably the bioavailability of Rifampicin is enhanced by preventing its degradation caused by presence of Isoniazid. Rifampicin and/or Isoniazid may be present in delayed release and/or extended release form such that minimal amount of the drug is dissolved between pH 1 and 4. preferably delayed release of Rifampicin and/or Isoniazid is achieved by treating the drugs with pH sensitive polymers.

Inventors:
Thing Amargit
Jane Rajesh
Application Number:
JP2002517064A
Publication Date:
February 26, 2004
Filing Date:
April 10, 2001
Export Citation:
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Assignee:
Panacea Biotech Limited
International Classes:
A61K9/08; A61K9/10; A61K9/14; A61K9/20; A61K9/22; A61K9/24; A61K9/28; A61K9/48; A61K9/50; A61K9/52; A61K31/4409; A61K31/495; A61K31/496; A61K45/00; A61K47/22; A61K47/32; A61K47/36; A61K9/06; A61K47/38; A61K47/46; A61P31/06; A61P43/00; (IPC1-7): A61K31/496; A61K9/06; A61K9/08; A61K9/10; A61K9/14; A61K9/20; A61K9/24; A61K9/28; A61K9/48; A61K31/4409; A61K47/22; A61K47/32; A61K47/36; A61K47/38; A61K47/46; A61P31/06; A61P43/00
Attorney, Agent or Firm:
Minoru Nakamura
Fumiaki Otsuka
Sadao Kumakura
Shishido Kaichi
Hideto Takeuchi
Toshio Imajo
Nobuo Ogawa
Village shrine Atsuo
Takaki Nishijima
Atsushi Hakoda
Kenji Asai