Title:
非ステロイド性抗炎症薬およびプロトンポンプ阻害薬を含有する医薬製剤
Document Type and Number:
Japanese Patent JP2004508396
Kind Code:
A
Abstract:
An oral solid dosage form includes a therapeutically effective amount of an NSAID and a proton pump inhibitor in an amount effective to inhibit or prevent gastrointestinal side effects normally associated with the NSAID. Also disclosed is a method of treating a human patient in need of antiinflammatory, analgesic and/or antipyretic therapy, comprising orally administering to the patient an oral pharmaceutical dosage form which includes a therapeutically effective amount of an NSAID and an amount of a proton pump inhibitor effective to substantially inhibit gastrointestinal side effects of the NSAID. The invention is further related to a method of prophylactically treating a human patient who is on a therapy known to have significant gastrointestinal side effects or is about to begin such a therapy, via concurrent administration of an NSAID and a proton pump inhibitor in a combination (single) oral dosage form.
Inventors:
Ji Min, Chen
Anchalee, Kositoprapa
Anchalee, Kositoprapa
Application Number:
JP2002526360A
Publication Date:
March 18, 2004
Filing Date:
September 10, 2001
Export Citation:
Assignee:
Andlux Corporation
International Classes:
A61K9/22; A61K9/24; A61K9/26; A61K9/30; A61K9/32; A61K9/34; A61K9/36; A61K9/48; A61K9/54; A61K9/58; A61K9/60; A61K9/62; A61K31/196; A61K31/415; A61K31/44; A61K31/4439; A61K45/00; A61K47/10; A61P15/00; A61P19/02; A61P29/00; A61P43/00; A61K9/28; A61K9/50; (IPC1-7): A61K31/196; A61K9/22; A61K9/24; A61K9/30; A61K9/48; A61K31/4439; A61K45/00; A61K47/10; A61P15/00; A61P19/02; A61P29/00; A61P43/00
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Yuko Matsuniya
Satoshi Fujita
Yuko Matsuniya