Title:
結合を検出するための13C-NMRの使用
Document Type and Number:
Japanese Patent JP2004510952
Kind Code:
A
Abstract:
Methods of detecting binding of a putative ligand to a 13C-enriched target molecule, methods of screening for compounds which bind to a 13C-enriched target molecule, methods for calculating the dissociation constant of a ligand compound which binds to a 13C-enriched target molecule, and methods employed in the determination of the specific amino acids in a 13C-enriched target molecule affected by the binding of a ligand, as well as compounds identified by these screening methods, are provided herewith.
Inventors:
Steve, Stephen Davryu
Heideuk, Philip Jei
Heideuk, Philip Jei
Application Number:
JP2000611085A
Publication Date:
April 08, 2004
Filing Date:
March 21, 2000
Export Citation:
Assignee:
ABBOTT LABORATORIES
International Classes:
G01N24/12; B08B9/04; C07K1/13; E21B37/04; G01N33/483; G01N33/50; G01N33/53; G01N33/542; G01N33/566; G01N33/68; G01N33/94; G01R33/46; G01R33/465; (IPC1-7): G01N33/483; G01N24/12; G01N33/50; G01N33/566; G01R33/465
Foreign References:
| WO1997018469A2 | 1997-05-22 | |||
| WO1997018471A1 | 1997-05-22 |
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Mitsuru Inoue
Akio Ichiiri
Katsuma Osaki
Takamasa Soma
Makoto Ono
Mitsuru Inoue
Akio Ichiiri
Katsuma Osaki
Takamasa Soma