Title:
粒子吸入キャリア
Document Type and Number:
Japanese Patent JP2004517834
Kind Code:
A
Abstract:
The present invention provides a particulate substrate suitable for carrying a drug for delivery, comprising a substantially crystalline core and a surface coating, wherein the particulate substrate has a proportion of amorphous character of 2% of greater by weight of particulate substrate, and a process for the production of carrier particles comprising the steps of: a) mixing crystalline particles having an average diameter greater than 10 mum with at least partially amorphous particles having average diameters less than 10 mum; b) exposing the mixture to conditions capable of inducing crystallization of the amorphous particles for a predetermined period in order that partial crystallization takes place.
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Inventors:
Buckton Graham
Al-hadici dima
Brocchini steven
Al-hadici dima
Brocchini steven
Application Number:
JP2002547468A
Publication Date:
June 17, 2004
Filing Date:
December 10, 2001
Export Citation:
Assignee:
School of Pharmacy, University of London
International Classes:
A61K9/00; A61K9/14; A61K9/72; A61K31/135; A61K31/137; A61K31/352; A61K31/7012; A61K38/00; A61K38/22; A61K38/28; A61K45/00; A61K47/26; A61L9/04; A61P11/00; A61P11/06; (IPC1-7): A61K47/26; A61K9/72; A61K31/135; A61K31/137; A61K31/352; A61K38/00; A61K38/22; A61K38/28; A61K45/00; A61P11/00; A61P11/06
Attorney, Agent or Firm:
Eiji Saegusa
Kakehi Yuro
Takeshi Ohara
Kenji Saito
Jun Fujii
Hitoshi Seki
Mutsuko Nakano
Kakehi Yuro
Takeshi Ohara
Kenji Saito
Jun Fujii
Hitoshi Seki
Mutsuko Nakano