Title:
人工転写因子および使用の方法
Document Type and Number:
Japanese Patent JP2004533804
Kind Code:
A
Abstract:
A description of artificial transcription factors (ATFs) is provided having a non-peptidic-DNA binding domain, flexible linker and a short synthetic effector domain. The ATFs are highly potent transcriptional modulators in vitro and in vivo. Methods for targeted manipulation of gene expression and the development of new class of pharmaceuticals are also provided.
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Inventors:
Stanojevic, Dusan
Application Number:
JP2002534533A
Publication Date:
November 11, 2004
Filing Date:
October 15, 2001
Export Citation:
Assignee:
Crosslink Genetics Corporation
International Classes:
C07K14/00; C12N15/113; C12N15/63; C12N15/09; C12Q1/02; (IPC1-7): C12N15/09; C07K14/00; C12Q1/02
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita