Title:
BACEのインヒビター
Document Type and Number:
Japanese Patent JP2004534017
Kind Code:
A
Abstract:
The present invention relates to inhibitors of aspartic proteinases, particularly, BACE. The present invention also relates to compositions thereof and methods therewith for inhibiting BACE activity in a mammal, and for treating Alzheimer's Disease and other BACE-mediated diseases.
Inventors:
Bisseti, Govinda Earl.
Sounders, Jeffrey Oh.
Murco, Mark A.
Lepre, Christopher A.
Brit, Shawn Dee.
Com, John H.
Deninger, David Dee.
Wang, Tian Shan
Sounders, Jeffrey Oh.
Murco, Mark A.
Lepre, Christopher A.
Brit, Shawn Dee.
Com, John H.
Deninger, David Dee.
Wang, Tian Shan
Application Number:
JP2002585403A
Publication Date:
November 11, 2004
Filing Date:
April 29, 2002
Export Citation:
Assignee:
VERTEX PHARMACEUTICALS INCORPORATED
International Classes:
A61K31/4409; A61K31/4439; A61K31/444; A61K31/47; A61K31/495; A61K31/496; A61K31/506; A61K31/55; A61K31/551; A61P25/28; C07D211/70; C07D211/72; C07D211/74; C07D211/82; C07D213/75; C07D217/26; C07D239/48; C07D241/04; C07D243/08; C07D295/12; C07D295/135; C07D401/04; C07D401/10; C07D401/12; C07D403/04; C07D405/10; C07D405/14; C07D487/04; (IPC1-7): C07D211/70; A61K31/4409; A61K31/4439; A61K31/444; A61K31/47; A61K31/495; A61K31/496; A61K31/506; A61K31/55; A61K31/551; A61P25/28; C07D211/72; C07D213/75; C07D239/48; C07D241/04; C07D243/08; C07D295/12; C07D401/04; C07D401/10; C07D403/04; C07D405/10; C07D405/14; C07D487/04
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita