コリン作用アップレギュレーション及び炎症ダウンレギュレーションを共誘導する化合物、並びにその使用

Title:

コリン作用アップレギュレーション及び炎症ダウンレギュレーションを共誘導する化合物、並びにその使用

Document Type and Number:

Japanese Patent JP2004537504

Kind Code:

A

Abstract:

Chimeric compounds are disclosed which are covalent conjugates of reversible or irreversible cholinergic up-regulators and non-steroidal anti-inflammatory drugs (NSAIDs), methods for their synthesis and use thereof for treatment and/or prevention of central nervous system (CNS) disorders and diseases.

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Inventors:

Gamitiel, Amitai
Rachel, Adan
Rabinowitz, Shy
Sodo-Morie, Galli
Meshram, heim

Application Number:

JP2002565538A

Publication Date:

December 16, 2004

Filing Date:

February 17, 2002

Export Citation:

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Assignee:

Israel Institute for Biological Research
Life Sciences Research Israel Limited

International Classes:

A61K31/405; A61K31/439; A61K31/4425; A61K31/4439; A61K31/455; A61P9/10; A61P25/00; A61P25/16; A61P25/28; C07D211/78; C07D213/65; C07D213/80; C07D401/12; C07D471/18; C07D211/74; (IPC1-7): C07D211/74; A61K31/439; A61K31/4425; A61K31/4439; A61K31/455; A61P9/10; A61P25/00; A61P25/16; A61P25/28; C07D211/78; C07D213/65; C07D213/80; C07D401/12; C07D471/18

Attorney, Agent or Firm:

Nobuaki Kazehaya
Noriko Asano

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