Title:
免疫応答のアジュバントとしてのケモカイン
Document Type and Number:
Japanese Patent JP2005502723
Kind Code:
A
Abstract:
Dendritic cells play a critical role in antigen-specific immune responses. Materials and Methods are provided for treating disease states, including cancer, infectious diseases, autoimmune diseases, transplantation, and allergy by facilitating or inhibiting the migration or activation of a specific subset of antigen-presenting dendritic cells known as plasmacytoid dendritic cells (pDC). In particular, methods for treating disease states are provided comprising administration of chemokine receptor agonists and antagonists, alone or in combination with a disease-associated antigen, with or without an activating agent.
Inventors:
Kor, Christoph
Bambell Briet, Bitlis
Karel Patrelle
Bicali, Alan
Transieri, Giorgio
Briere, Francine
Bandori-Belle Mar, Natali
Bambell Briet, Bitlis
Karel Patrelle
Bicali, Alan
Transieri, Giorgio
Briere, Francine
Bandori-Belle Mar, Natali
Application Number:
JP2003528502A
Publication Date:
January 27, 2005
Filing Date:
September 19, 2002
Export Citation:
Assignee:
Schering Corporation
International Classes:
C12N5/07; A61K38/00; A61K38/19; A61K39/00; A61K39/02; A61K39/12; A61K39/35; A61K39/39; A61K45/00; A61P31/04; A61P31/10; A61P31/12; A61P33/00; A61P35/00; A61P37/00; A61P37/06; A61P37/08; A61P43/00; C12N5/077; C12N5/0783; C12N5/0784; C12N5/09; (IPC1-7): A61K45/00; A61K38/00; A61K39/00; A61K39/02; A61K39/12; A61K39/35; A61P31/04; A61P31/10; A61P31/12; A61P33/00; A61P35/00; A61P37/00; A61P37/06; A61P37/08; A61P43/00
Domestic Patent References:
| JP2000514295A | 2000-10-31 | |||
| JP2001513629A | 2001-09-04 | |||
| JPH11509187A | 1999-08-17 | |||
| JPH09506774A | 1997-07-08 | |||
| JPH08501085A | 1996-02-06 | |||
| JP2008133296A | 2008-06-12 |
Foreign References:
| WO2000003728A1 | 2000-01-27 | |||
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Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita