Title:
疎水性物質の薬物動態学的プロファイルの増大
Document Type and Number:
Japanese Patent JP2005503359
Kind Code:
A
Abstract:
A method for systemic administration of a hydrophobic substance to a mammal is disclosed. The method involves delivering the hydrophobic substance to the dermis of the mammal whereby improved systemic absorption is obtained compared to absorption produced upon delivering the substance subcutaneously by bolus administration.
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Inventors:
Pinkerton, Thomas Sea
Application Number:
JP2003508333A
Publication Date:
February 03, 2005
Filing Date:
June 24, 2002
Export Citation:
Assignee:
Pharmacia Corporation
International Classes:
A61K9/14; A61K9/70; A61K31/351; A61K31/395; A61K31/415; A61K31/42; A61K31/4433; A61K31/4745; A61K9/08; A61K31/727; A61K38/00; A61K38/22; A61K38/23; A61K38/27; A61K38/28; A61K45/00; A61M37/00; A61N1/30; A61P5/06; A61P25/16; A61K9/00; (IPC1-7): A61K9/08; A61K9/14; A61K31/351; A61K31/415; A61K31/42; A61K31/4433; A61K31/4745; A61K38/00; A61K45/00
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroko Ejiri
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroko Ejiri