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Title:
ピペリジン誘導体、これの製造方法及びこれを含む痴呆治療用薬学的組成物
Document Type and Number:
Japanese Patent JP2005505626
Kind Code:
A
Abstract:
The present invention relates to novel piperidine derivatives having effect of inhibiting acetylcholinesterase and aggregation of beta-amyloid, Alzheimer's disease-induced protein, and treatment for Alzheimer's disease containing the same, the piperidine derivatives represented by Formula 3.

Inventors:
Kwon Young Yi
Kang Zhong Ho
Reference
Lisanze
Kind one
Rikanfun
Han Sung Il
Yoon Yoo Sung
Application Number:
JP2003536229A
Publication Date:
February 24, 2005
Filing Date:
October 16, 2002
Export Citation:
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Assignee:
Esteey Nara Company Limited
International Classes:
C07D211/44; A61K31/445; A61K31/453; A61P25/28; C07D211/46; C07D401/12; (IPC1-7): C07D211/46; A61K31/445; A61K31/453; A61P25/28; C07D401/12
Domestic Patent References:
JPH07109275A1995-04-25
JP2000501117A2000-02-02
JP2001139547A2001-05-22
JPS625956A1987-01-12
JP2005529840A2005-10-06
Other References:
DOODY R.S.: "Clinical", EUROPEAN NEUROPSYCHOPHARMACOLOGY, vol. 9, JPN6008036031, 1999, pages 69 - 77, ISSN: 0001091898
ZHAO等: "Synthesis of 1,2-Diamino and 1,2-Aminoalcohol Derivatives in the Piperidine and Pyrrolidine Series a", BIOOGANIC AND MEDICINAL CHEMISTRY, vol. 7(8), JPN6008036032, 1999, pages 1647 - 1654, ISSN: 0001091899
Attorney, Agent or Firm:
Sakuo Yamaguchi