Title:
ヒトcDNAおよびタンパク質、ならびにそれらの使用
Document Type and Number:
Japanese Patent JP2005508141
Kind Code:
A
Abstract:
The invention provides polynucleotides and polypeptides encoding an isolated amyloid inhibitor protein (APIP) and compositions thereof. The polypeptides of the subject invention can be used to inhibit the catabolism or sequential cleavage of amyloid beta precursor protein (APP) by sequential cleavage of APP by beta secretase and gamma secretase.
Inventors:
Bejanin, stefan
Tanaka, Hiroaki
Tanaka, Hiroaki
Application Number:
JP2002592338A
Publication Date:
March 31, 2005
Filing Date:
August 06, 2001
Export Citation:
Assignee:
Serono Genetics Institute Societe Anim
International Classes:
A61K45/00; A61P35/00; A61P35/02; A61P35/04; A61P43/00; C07K14/47; C07K16/18; C12N15/09; C12N15/12; C12P21/02; C12Q1/68; G01N33/15; G01N33/50; G01N33/53; G01N33/566; A61K38/00; A61K48/00; (IPC1-7): C12N15/09; A61K45/00; A61P35/00; A61P35/02; A61P35/04; A61P43/00; C07K14/47; C07K16/18; C12P21/02; C12Q1/68; G01N33/15; G01N33/50; G01N33/53; G01N33/566
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Ishii Teiji
Satoshi Fujita