Title:
3-アミド-1,2-ベンゾイソオキサゾール誘導体、その塩の製造方法及び使用
Document Type and Number:
Japanese Patent JP2005508987
Kind Code:
A
Abstract:
The present invention relates to 3-amido-1,2-benzoisoxazole derivatives and their salts represented by formula 1, processes for preparation and usees thereof. More particularly, it relates to a method for improving its bioavailability introducing amino acid residue to the amine group of a 3-amido-1,2-benzoisoxazole. The compounds according to the present invention are used as an antagonist against Leukotriene-B-4 receptor, an inhibitor or therapeutics of osteoroposis, thus inhibiting osteolysis and stimulating osteogensis.
Inventors:
Lee, Jins
Anne, Sukhon
Jin, Yunk
Jin, Sanmi
Ku, second
Les, Cheyman
Chan, Yongho
Kim, Yunju
Cho, Sunki
Anne, Sukhon
Jin, Yunk
Jin, Sanmi
Ku, second
Les, Cheyman
Chan, Yongho
Kim, Yunju
Cho, Sunki
Application Number:
JP2003542159A
Publication Date:
April 07, 2005
Filing Date:
November 05, 2002
Export Citation:
Assignee:
DONG WHA PHARM.IND.CO.,LTD
International Classes:
A61K31/423; A61P19/10; C07D261/20; (IPC1-7): C07D261/20; A61K31/423; A61P19/10
Attorney, Agent or Firm:
Hironobu Onda
Makoto Onda
Makoto Onda