Title:
乳癌の予防において使用するためのビス(シアノフェニル)メチル-トリアゾール
Document Type and Number:
Japanese Patent JP2005515207
Kind Code:
A
Abstract:
The present invention relates to the use of a lower dosage of bis(cyanophenyl)methyl-triazole of the formula (I) or a pharmaceutically acceptable salts thereof, for the preparation of a pharmaceutical composition for the prevention of conditions responsive to aromatase inhibition and to inhibition of estrogen biosynthesis, especially breast cancer, in mammals.
Inventors:
Rajeshwar Rao Techmal
Application Number:
JP2003551118A
Publication Date:
May 26, 2005
Filing Date:
December 10, 2002
Export Citation:
Assignee:
Emory University
International Classes:
A61K31/4196; A61P35/00; A61P43/00; C07D249/08; (IPC1-7): A61K31/4196; A61P35/00; A61P43/00; C07D249/08
Other References:
JPN6009065874, Ｅｎｄｏｃｒｉｎｅ−Ｒｅｌａｔｅｄ Ｃａｎｃｅｒ, 1999, Ｖｏｌ．６, ｐ．３０７−３１４
JPN6009065875, Ｃａｎｃｅｒ Ｒｅｓｅａｒｃｈ, 20010301, Ｖｏｌ．６１, ｐ．１９１０−１９１８
JPN6009065878, 内分泌・糖尿病科, 2000, Ｖｏｌ．１０， Ｎｏ．１, ｐ．７７−８２
JPN6009065876, Ａｃｔａ Ｏｎｃｏｌｏｇｉｃａ, 1996, Ｖｏｌ．３５， Ｓｕｐｐｌ．５, ｐ．１５−１８
JPN6009065877, Ｊｏｕｒｎａｌ ｏｆ Ｃｌｉｎｉｃａｌ Ｅｎｄｏｃｒｉｎｏｌｏｇｙ ａｎｄ Ｍｅｔａｂｏｌｉｓｍ, 1993, Ｖｏｌ．７７， Ｎｏ．２, ｐ．３１９−３２３
JPN6009065875, Ｃａｎｃｅｒ Ｒｅｓｅａｒｃｈ, 20010301, Ｖｏｌ．６１, ｐ．１９１０−１９１８
JPN6009065878, 内分泌・糖尿病科, 2000, Ｖｏｌ．１０， Ｎｏ．１, ｐ．７７−８２
JPN6009065876, Ａｃｔａ Ｏｎｃｏｌｏｇｉｃａ, 1996, Ｖｏｌ．３５， Ｓｕｐｐｌ．５, ｐ．１５−１８
JPN6009065877, Ｊｏｕｒｎａｌ ｏｆ Ｃｌｉｎｉｃａｌ Ｅｎｄｏｃｒｉｎｏｌｏｇｙ ａｎｄ Ｍｅｔａｂｏｌｉｓｍ, 1993, Ｖｏｌ．７７， Ｎｏ．２, ｐ．３１９−３２３
Attorney, Agent or Firm:
Aoyama Aoi
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima