Title:
細胞増殖を調節する化合物
Document Type and Number:
Japanese Patent JP2005515252
Kind Code:
A
Abstract:
The following compounds of formulae (I) and (III) which may be useful in treating a variety of cell proliferative disorders are disclosed: Formula (I), (II), wherein R1, R2 and R3 are each independently selected from H, OH, C1-6alkyl, C1-6alkoxy, NH2, NH-C1-6alkyl, N(C1-6alkyl), SH, S-C1-6alkyl, NO2, CF3, OCF3 and halo; R4 is unsubstituted Ar, or Ar substituted with 1-4 substituents, independently selected from C1-6alkyl, C1-6alkoxy and halo; X is selected from (CH2CH2O)n and (CH2)n, and n=1-4.
Inventors:
Royfman Chime M.
Demin Peter
Gran Burger Thomas
Ronova Olga
Chimpene Octavian Roland
Demin Peter
Gran Burger Thomas
Ronova Olga
Chimpene Octavian Roland
Application Number:
JP2003562074A
Publication Date:
May 26, 2005
Filing Date:
January 17, 2003
Export Citation:
Assignee:
THE HOSPITAL FOR SICK CHILDREN
International Classes:
A61K31/165; A61K31/216; A61K31/222; A61K31/265; A61K31/277; A61K31/4402; A61P35/00; C07D213/70; A61P35/02; C07C255/23; C07C255/38; C07C255/41; C07C309/67; C07C309/73; C07C317/44; C07C317/46; (IPC1-7): C07C255/41; A61K31/277; A61K31/4402; A61P35/00; C07C317/44; C07C317/46; C07D213/70
Attorney, Agent or Firm:
Hatsushi Shimizu
Kazunori Hashimoto
Koichi Niimi
Kazunori Hashimoto
Koichi Niimi