Title:
アデノシンデアミナーゼ阻害活性を有するイミダゾール-4-カルボキサミド
Document Type and Number:
Japanese Patent JP2005517706
Kind Code:
A
Abstract:
Imidazole compounds having adenosine deaminase inhibitory activity represented by the formula (I): wherein R1 is optionally substituted aryl or optionally substituted heteroaryl, R2 is lower alkyl; R3 is hydroxy or protected hydroxy; X is O or S; and -A- is lower alkylene, its prodrug, or their salt. The compounds are useful for treating and/or preventing diseases for which adenosine is effective.
Inventors:
Kira Tsuji
Terasaka
Konishi Nobuyoshi
Takeshi Kato
Katsuya Nakamura
Terasaka
Konishi Nobuyoshi
Takeshi Kato
Katsuya Nakamura
Application Number:
JP2003567895A
Publication Date:
June 16, 2005
Filing Date:
February 12, 2003
Export Citation:
Assignee:
Fujisawa Pharmaceutical Co., Ltd.
International Classes:
A61K31/423; A61K45/00; A61P1/06; A61P25/00; A61P25/04; A61P29/00; A61P35/02; A61P37/00; A61P37/06; A61P43/00; C07D403/06; C07D405/06; C07D409/14; C07D413/06; C07D413/14; C07D417/06; (IPC1-7): C07D413/06; A61K31/423; A61K45/00; A61P1/06; A61P25/00; A61P25/04; A61P29/00; A61P35/02; A61P37/00; A61P37/06; A61P43/00; C07D413/14; C07D417/06
Attorney, Agent or Firm:
Eiji Tafushi
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