Title:
デフェンシン:抗ウイルス剤の使用
Document Type and Number:
Japanese Patent JP2005527235
Kind Code:
A
Abstract:
The present invention relates to inhibition of viruses, e.g., HIV, using defensins. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions, antibodies, peptides, nucleic acids, antisense nucleic acids, and ribozymes, that increase naturally occurring defensin expression or activity, thereby inhibiting HIV in a cell; as well as to the use of expression profiles and compositions in diagnosis and prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.
Inventors:
Zan, Lynch
Ho, David Dee.
Kuffrey, Rebecca E.
Dalmasso, Enrique A.
May, Janphen
Ho, David Dee.
Kuffrey, Rebecca E.
Dalmasso, Enrique A.
May, Janphen
Application Number:
JP2004508752A
Publication Date:
September 15, 2005
Filing Date:
May 30, 2003
Export Citation:
Assignee:
Ciphergen Biosystems, Inc.
Aaron Diamond AIDS Research Center
Aaron Diamond AIDS Research Center
International Classes:
C12N15/09; A61K38/00; A61K38/17; A61K45/00; A61K48/00; A61P31/18; C07K14/47; C07K16/18; C07K19/00; C12N5/07; C12N5/071; C12N5/0789; C12Q1/02; C12Q1/68; C12Q1/70; G01N33/543; G01N33/569; (IPC1-7): C12N15/09; A61K38/00; A61K45/00; A61K48/00; A61P31/18; C07K14/47; C07K19/00; C12N5/06; C12Q1/02; C12Q1/68; C12Q1/70
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita