Title:
核転写調節因子NF-κB抑制剤と抗腫瘍薬の相乗効果
Document Type and Number:
Japanese Patent JP2005529123
Kind Code:
A
Abstract:
The present invention provides methods of inhibiting metastasis of a tumor and methods of treating a tumor using a combination of an inhibitor of the activation of nuclear factor NF-kappaB and a cancer chemotherapeutic agent. In one embodiment of the present invention, combination of curcumin and paclitaxel (taxol) can be used to treat and inhibit metastasis of breast tumor.
Inventors:
Agawar, Barat
Application Number:
JP2003587320A
Publication Date:
September 29, 2005
Filing Date:
April 24, 2003
Export Citation:
Assignee:
RESEARCH DEVELOPMENT FOUNDATION
International Classes:
A61K45/06; A61K31/05; A61K31/12; A61K31/16; A61K31/337; A61K31/44; A61K31/454; A61K31/525; A61P35/04; A61P43/00; (IPC1-7): A61K45/06; A61K31/12; A61K31/337; A61P35/04; A61P43/00
Domestic Patent References:
| JPH10500657A | 1998-01-20 | |||
| JP2000505796A | 2000-05-16 | |||
| JPH1192363A | 1999-04-06 | |||
| JPH11322602A | 1999-11-24 | |||
| JPH10175861A | 1998-06-30 | |||
| JPH1171278A | 1999-03-16 | |||
| JP2000169479A | 2000-06-20 |
Foreign References:
| WO2000030587A2 | 2000-06-02 | |||
| WO2001040188A1 | 2001-06-07 |
Other References:
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PHARMACOL. RES., vol. 39, JPN6009024043, 1999, pages 175 - 9, ISSN: 0001325694
INT. J. CLIN. ONCOL., vol. 6, JPN6009024044, 2001, pages 55 - 8, ISSN: 0001325695
Attorney, Agent or Firm:
Igarashi Kazutoshi