Title:
アミロイドβペプチドに対する特異性抗体、医薬組成物、及びその使用方法
Document Type and Number:
Japanese Patent JP2005531509
Kind Code:
A
Abstract:
The invention relates to methods of treating a subject having Alzheimer's Disease, comprising the step of administering an antibody molecule which is targeted to β amyloid peptide or to fragment thereof. In another embodiment the invention relates to methods of treating a disease or a disorder, characterized by amyloid beta deposition. In another embodiment, the invention relates to an antibody molecule, which is free end-specific for the N-terminus or the C-terminus of an amyloid β peptide and to a pharmaceutical composition thereof. In another embodiment, the invention relates to an antibody molecule, which is targeted to the free C or N-terminus of a N- and/or C-terminus truncated amyloid β peptide fragment.
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Inventors:
Chain, Daniel G
Application Number:
JP2003572597A
Publication Date:
October 20, 2005
Filing Date:
October 21, 2002
Export Citation:
Assignee:
MINDSET BIOPHARMACEUTICALS USA INC.
International Classes:
A61K39/395; A61P25/28; C07K14/47; C07K16/18; C12P21/08; A61K48/00; (IPC1-7): A61K39/395; A61P25/28; C07K16/18
Attorney, Agent or Firm:
Yoichi Oshima