Title:
細胞外マトリックスの製造方法および腫瘍細胞培養のためのその使用
Document Type and Number:
Japanese Patent JP2005533512
Kind Code:
A
Abstract:
The invention concerns a method for preparing an isolated extracellular matrix, secreted by tumor cells, in particular epitheliomatous cells, methods for tumor cell culture using such a matrix, the use of such a matrix for producing a tumor cell line as well as novel tumor cell lines obtained by said method. The invention also concerns a method for selecting a compound capable of inhibiting the growth and/or proliferation of tumor cells, the use of said compounds as medicine for cancer treatment as well as a diagnosis or prognosis method in vitro by chromosomal analysis using said matrices. The invention further concerns a reactor or a kit for cell culture comprising such an extracellular matrix.
Inventors:
Jean, Benard
Application Number:
JP2004523893A
Publication Date:
November 10, 2005
Filing Date:
July 28, 2003
Export Citation:
Assignee:
INSTITUT GUSTAVE-ROUSSY
International Classes:
C12N15/09; C07G99/00; C12M3/00; C12N5/02; C12N5/09; C12P1/00; C12Q1/02; C12Q1/68; (IPC1-7): C12N5/06; C07G17/00; C12M3/00; C12P1/00; C12Q1/02; C12Q1/68
Attorney, Agent or Firm:
Kenji Yoshitake
Yukitaka Nakamura
Konno Akio
Noritaka Yokota
Yukitaka Nakamura
Konno Akio
Noritaka Yokota