Title:
非ペプチドレニン阻害薬及び界面活性剤を含有する医薬製剤
Document Type and Number:
Japanese Patent JP2005533816
Kind Code:
A
Abstract:
Composition comprising (1) a non-peptide renin inhibitor which is poorly soluble to readily soluble in water and (2) at least one physiologically tolerated anionic surfactant, at least one physiologically tolerated amphoteric surfactant at least one physiologically tolerated neutral surfactant, or a mixture of at least two of these surfactants, with the quantity of readily soluble renin inhibitor being at least 10% by weight, and the quantity of a poorly soluble renin inhibitor being at least 35% by weight based on the composition. In oral administration forms, the composition exhibits increased bioavailability.
Inventors:
Reedre, Yutta
Canner, satish
Dieterle, Walter
Canner, satish
Dieterle, Walter
Application Number:
JP2004516786A
Publication Date:
November 10, 2005
Filing Date:
June 25, 2003
Export Citation:
Assignee:
SPEEDEL PHARMA AG
International Classes:
A61K47/14; A61K31/165; A61K31/195; A61K31/415; A61K31/4172; A61K31/425; A61K31/451; A61K31/4709; A61K31/496; A61K45/08; A61K47/20; A61K47/24; A61K47/34; A61P9/00; A61P9/12; A61P43/00; (IPC1-7): A61K45/08; A61K31/165; A61K31/4172; A61K31/451; A61K31/4709; A61K31/496; A61K47/14; A61K47/20; A61K47/24; A61K47/34; A61P9/00; A61P9/12; A61P43/00
Foreign References:
| WO2002040007A1 | 2002-05-23 |
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda
Fumio Shinoda