Title:
治療的処置のための組成物および方法
Document Type and Number:
Japanese Patent JP2005534679
Kind Code:
A
Abstract:
The present invention relates to compositions utilizing an agent and an antibody, or fragment thereof. In these compositions, the agents, including agents such as anti-cancer, anti-metastasis, anti-leukemia, anti-disease, anti-adhesion, anti-thrombosis, anti -restenosis, anti-autoimmune, anti-aggregation, anti-bacterial, anti-viral, and anti-inflammatory agents, can be complexed or combined with or conjugated to the antibodies, or fragments thereof. In addition, the agent and/or the antibody, or fragment thereof, can be present in the composition in a sub-clinical amount, which is an amount that is less than the amount of the agent generally found to be clinically effective when the agent is administered alone. Preferably, in these compositions of the present invention, the agent is an anthracycline or a derivative thereof, e.g., doxorubicin (adriamycin) or a derivative thereof.
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Inventors:
Lazarovitz, Janet
Nimrod, Abraham
Hosh-Ma-Chime, Hagit
Lebanon, Abigeau
Nimrod, Abraham
Hosh-Ma-Chime, Hagit
Lebanon, Abigeau
Application Number:
JP2004518133A
Publication Date:
November 17, 2005
Filing Date:
June 30, 2003
Export Citation:
Assignee:
Survival Pharmaceuticals, Incorporated
International Classes:
A61K31/704; A61K39/395; A61K47/48; A61K51/00; A61P7/02; A61P9/00; A61P29/00; A61P35/00; A61P35/02; A61P35/04; A61P37/06; A61K45/00; A61P43/00; C07K16/30; (IPC1-7): A61K45/00; A61K39/395; A61K51/00; A61P7/02; A61P9/00; A61P29/00; A61P35/00; A61P35/02; A61P35/04; A61P37/06; A61P43/00
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama