Title:
EP4受容体作動薬、組成物及びその方法
Document Type and Number:
Japanese Patent JP2005537235
Kind Code:
A
Abstract:
This invention relates to potent selective agonists of the EP4 subtype of prostaglandin E2 receptors, their use or a formulation thereof in the treatment of glaucoma and other conditions which are related to elevated intraocular pressure in the eye of a patient.
Inventors:
Billow, xavier
Robert N, Young
Han, Young Shin
Robert N, Young
Han, Young Shin
Application Number:
JP2004510890A
Publication Date:
December 08, 2005
Filing Date:
June 02, 2003
Export Citation:
Assignee:
Merck Frost Canada and Company
International Classes:
C07D403/06; A61K31/13; A61K31/137; A61K31/138; A61K31/382; A61K31/4015; A61K31/41; A61K31/416; A61K31/4164; A61K31/4168; A61K31/4178; A61K31/433; A61K31/4412; A61K31/498; A61K31/5377; A61K31/5575; A61K31/559; A61K45/00; A61K45/06; A61P3/14; A61P19/00; A61P19/02; A61P19/08; A61P19/10; A61P25/02; A61P27/02; A61P27/06; A61P29/00; A61P35/00; A61P43/00; C07D207/26; C07D403/12; (IPC1-7): A61K31/4015; A61K31/13; A61K31/137; A61K31/138; A61K31/382; A61K31/41; A61K31/416; A61K31/4164; A61K31/4168; A61K31/4178; A61K31/433; A61K31/4412; A61K31/498; A61K31/5377; A61K31/5575; A61K31/559; A61K45/00; A61P3/14; A61P19/00; A61P19/02; A61P19/08; A61P19/10; A61P25/02; A61P27/02; A61P27/06; A61P29/00; A61P35/00; A61P43/00; C07D403/06; C07D403/12
Domestic Patent References:
| JP2000053566A | 2000-02-22 | |||
| JPS6147459A | 1986-03-07 | |||
| JP2001509485A | 2001-07-24 |
Foreign References:
| WO2002024647A1 | 2002-03-28 | |||
| WO2002042268A2 | 2002-05-30 | |||
| WO2000038667A2 | 2000-07-06 | |||
| WO2000003980A1 | 2000-01-27 |
Other References:
JPN6009044601, Ｃ．Ｇ．ＷＥＲＭＵＴＨ編，長瀬博 監訳, 最新 創薬化学 上巻, 1998, ｐ．２４８−２５２, 株式会社 テクノミック
JPN6010009414, Ｃ．Ｇ．ＷＥＲＭＵＴＨ 編， 長瀬博 監訳, 最新 創薬化学 上巻, 1998, ｐ．２６１, 株式会社 テクノミック
JPN6010009414, Ｃ．Ｇ．ＷＥＲＭＵＴＨ 編， 長瀬博 監訳, 最新 創薬化学 上巻, 1998, ｐ．２６１, 株式会社 テクノミック
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura