Title:
GFAT発現のアンチセンス調節
Document Type and Number:
Japanese Patent JP2006502736
Kind Code:
A
Abstract:
Antisense compounds, compositions, and methods are provided for modulating the expression of Glutamine-fructose-6-phosphate amidotransferase (GFAT). The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding GFAT. Methods of using these compounds for modulation of GFAT expression and for treatment of diseases associated with expression of GFAT are provided.
Inventors:
Broschat, Kaye O
Crosby, Seth Dee
Crosby, Seth Dee
Application Number:
JP2004545576A
Publication Date:
January 26, 2006
Filing Date:
October 02, 2003
Export Citation:
Assignee:
Pharmacia Corporation
International Classes:
C12N15/09; A61K31/7115; A61K31/712; A61K31/7125; A61K48/00; A61P3/04; A61P3/10; A61P9/00; A61P9/10; A61P25/00; A61P43/00; C07H21/02; C12N15/113; A61K38/00
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hisako Nozaki
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hisako Nozaki