Title:
タンパク質の修飾
Document Type and Number:
Japanese Patent JP2006503091
Kind Code:
A
Abstract:
The present invention relates to a method for changing the half-life of a glycosylated compound by the modification of its O-linked carbohydrates. This modification is preferably carried out enzymatically and aimed at extending the half-life of the compound. Both in vivo and in vitro modification protocols may be used.
Inventors:
Van Berkel, Patrick
Monesse, Maurice
Piper, Frank
Monesse, Maurice
Piper, Frank
Application Number:
JP2004545078A
Publication Date:
January 26, 2006
Filing Date:
October 17, 2003
Export Citation:
Assignee:
Farming Intellectual Property B.V.
International Classes:
A61K38/00; A61K38/17; A61K38/55; A61P43/00; C07K14/81; C12N9/10; C12N15/09; C12P19/00; C12P19/44; C12P21/00; C12P21/02; C12N9/99
Domestic Patent References:
| JP2001507215A | 2001-06-05 |
Foreign References:
| WO1992022320A1 | 1992-12-23 |
Attorney, Agent or Firm:
Takehiko Suzue
Satoshi Kono
Makoto Nakamura
Kurata Masatoshi
Takashi Mine
Yoshihiro Fukuhara
Toshio Shirane
Sadao Muramatsu
Nobuhisa Nogawa
Ryo Hashimoto
Tetsuya Kazama
Satoshi Kono
Makoto Nakamura
Kurata Masatoshi
Takashi Mine
Yoshihiro Fukuhara
Toshio Shirane
Sadao Muramatsu
Nobuhisa Nogawa
Ryo Hashimoto
Tetsuya Kazama