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Patent Searching and Data


Title:
精製方法
Document Type and Number:
Japanese Patent JP2006506216
Kind Code:
A
Abstract:
The present invention relates to methods of processing of chemical samples containing compounds or molecular complexes using a binding material comprising a method of separating a compound or molecular complex on the basis of the ability of the compound or molecular complex to associate with a binding material, from compounds or molecular complexes having different association characteristics, said method comprising: (a) bringing a sample containing said compound or molecular complex into contact with a binding material, the binding material comprising: (i) a support, (ii) at least one terminal moiety selected from the group consisting of lecithins, lysolecithins, cephalins, sphingomyelin, cardiolipin, glycolipids, gangliosides, cerebrosides and phospholipids, and (iii) at least one linker of the formula (I) wherein R1 and R2 may be the same or different and are independently selected from the group consisting of: H, OH, C1-C6 alkyl, C2-C6 alkenyl, halogen, C1-C6 alkoxy, C2-C6 alkenyloxy and aryloxy, or R1 or R2 when taken together with an R1 or R2 on an adjacent linker forms a group of formula -O-, wherein said group -O- connects the silicon atom of the linker to the silicon atom of the adjacent linker, R3 and R4 may be the same or different and are independently selected from the group consisting of H, C1-C6 alkyl, C2-C6 alkenyl and halogen, R5 is H or C1-C6 alkyl, R6 is H, C1-C6 alkyl, C2-C6 alkenyl, aryl and heteroaryl, X is O or S, n is an integer from 0 to 10, the terminal moiety being bound to the support via at least one linker, (b) treating the product of step (a) to separate the components of the sample on the basis of their ability to associate with the binding material.

Inventors:
Lee, Zhong-Shen
Pearl matter, patrick
Aguilar, Marie-Isabel
Application Number:
JP2004518264A
Publication Date:
February 23, 2006
Filing Date:
July 02, 2003
Export Citation:
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Assignee:
Monash University
International Classes:
B01D15/38; B01J20/281; B01J20/283; B01J20/284; B01J20/285; B01J20/286; C07K1/16; G01N30/26; G01N30/34; G01N30/88; B01J20/32
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Takashi Nakata