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Title:
CCR5拮抗薬としてのピロリジンおよびアゼチジン化合物
Document Type and Number:
Japanese Patent JP2006511552
Kind Code:
A
Abstract:
The present invention relates to compounds of formula (I), or pharmaceutically acceptable derivatives thereof, useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).

Inventors:
Yang, Hambiao
Kazumielski, Weaslow, Meetslow
Aquino, Christopher, Joseph
Application Number:
JP2004560830A
Publication Date:
April 06, 2006
Filing Date:
December 12, 2003
Export Citation:
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Assignee:
SmithKline Beechham Corporation
International Classes:
C07D471/10; A61K31/438; A61K45/00; A61P1/04; A61P3/10; A61P9/10; A61P11/06; A61P13/12; A61P17/00; A61P17/02; A61P19/08; A61P21/04; A61P25/00; A61P25/28; A61P27/16; A61P29/00; A61P31/00; A61P31/04; A61P31/12; A61P31/18; A61P35/00; A61P37/02; A61P37/06; A61P37/08
Domestic Patent References:
JPH09500361A1997-01-14
Foreign References:
WO1995028389A11995-10-26
Other References:
ROY J. VAZ, ET AL., BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 7(22), JPN6010023258, 1997, pages 2825 - 2830, ISSN: 0001605089
TIMOTHY P. BURKHOLDER, ET AL., BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 6(8), JPN6010023259, 1996, pages 951 - 956, ISSN: 0001605090
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita