Title:
水性種の合成核酸
Document Type and Number:
Japanese Patent JP2006512098
Kind Code:
A
Abstract:
A synthetic nucleic acid molecule is provided that includes nucleotides of a coding region for a fluorescent polypeptide having a codon composition differing at more than 25% of the codons from a parent nucleic acid sequence encoding a fluorescent polypeptide. The synthetic nucleic acid molecule has at least 3-fold fewer transcription regulatory sequences relative to the average number of such sequences in the parent nucleic acid sequence. The polypeptide encoded by the synthetic nucleic acid molecule preferably has at least 85% sequence identity to the polypeptide encoded by the parent nucleic acid sequence.
Inventors:
Almond, brian, dee
Wood, monica, gee
Wood, keith, vie
Wood, monica, gee
Wood, keith, vie
Application Number:
JP2005513754A
Publication Date:
April 13, 2006
Filing Date:
November 20, 2003
Export Citation:
Assignee:
Promega Corporation
International Classes:
C12N15/09; C07H21/04; C07K14/435; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/02; C12N15/00; C12N15/10; C12N15/12; C12N15/67; C12N15/85; C12R1/91
Foreign References:
| WO2002016944A2 | 2002-02-28 |
Other References:
GENBANK ACCESSION: AY037769, JPN6007007017, ISSN: 0000924702
GENBANK ACCESSION: AY037768, JPN6007007016, ISSN: 0000924703
GENBANK ACCESSION: AF406766, JPN6007007014, ISSN: 0000924704
GENBANK ACCESSION: AF401282, JPN6007007012, ISSN: 0000924705
GENBANK ACCESSION: AY037768, JPN6007007016, ISSN: 0000924703
GENBANK ACCESSION: AF406766, JPN6007007014, ISSN: 0000924704
GENBANK ACCESSION: AF401282, JPN6007007012, ISSN: 0000924705
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Junko Kobayashi
Norio Omori
Eiji Katayama
Junko Kobayashi
Norio Omori