N-11短縮化アミロイド-ベータモノクローナル抗体、組成物、方法および使用 - JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP

Title:

N-11短縮化アミロイド-ベータモノクローナル抗体、組成物、方法および使用

Document Type and Number:

Japanese Patent JP2006513988

Kind Code:

A

Abstract:

This invention relates to antibodies, including specified portions or variants, specific for at least the human Amyloid-beta 11 N-terminal site, i.e. Aβ11-x peptides. It further provides methods of making and using said antibodies, including therapeutic formulations, administration and devices.

Inventors:

Marken, Mark Hubert
Vandermerlen, Marc Maria Pierre Perazier

Application Number:

JP2004538886A

Publication Date:

April 27, 2006

Filing Date:

September 09, 2003

Export Citation:

Click for automatic bibliography generation Help

Assignee:

JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP

International Classes:

C07K16/18; C12N5/10; C12N5/18; C12N5/20; G01N33/53; G01N33/68; A61K39/395; A61P9/00; A61P25/28; C12N15/09; C12P21/08

Foreign References:

WO2001062801A2	2001-08-30
WO2002047466A2	2002-06-20
WO2001062801A2	2001-08-30
WO2002047466A2	2002-06-20

Other References:

JPN5005007590; ＳＡＩＤＯ　ＴＡＫＡＯＭＩ　Ｃ: ＮＥＵＲＯＳＣＩＥＮＣＥ　ＬＥＴＴＥＲＳＶ２１５　Ｎ３, 1996, Ｐ１７３-１７６
JPN6009067744; Ｊ．　Ｂｉｏｌ．　Ｃｈｅｍ．，　２００２．Ｍａｙ，　Ｖｏｌ．２７７，　Ｎｏ．１８，　ｐｐ．１６２７８-１６２８４
JPN6009067695; Ｐｒｏｃ．　Ｎａｔｌ．　Ａｃａｄ．　Ｓｃｉ．　ＵＳＡ，　１９９６，　Ｖｏｌ．９３，　ｐｐ．４５２-４５５
JPN6013062740; Ｂｉｏｃｈｅｍｉｓｔｒｙ（２００２），Ｖｏｌ．４１，ｐ．３１２８-３１３６ , 2002
JPN5005007590; ＳＡＩＤＯ　ＴＡＫＡＯＭＩ　Ｃ: ＮＥＵＲＯＳＣＩＥＮＣＥ　ＬＥＴＴＥＲＳＶ２１５　Ｎ３, 1996, Ｐ１７３-１７６
JPN6009067744; Ｊ．　Ｂｉｏｌ．　Ｃｈｅｍ．，　２００２．Ｍａｙ，　Ｖｏｌ．２７７，　Ｎｏ．１８，　ｐｐ．１６２７８-１６２８４
JPN6009067695; Ｐｒｏｃ．　Ｎａｔｌ．　Ａｃａｄ．　Ｓｃｉ．　ＵＳＡ，　１９９６，　Ｖｏｌ．９３，　ｐｐ．４５２-４５５

Attorney, Agent or Firm:

Heikichi Odashima

Previous Patent: プロピレンのプロピレンオキシドへの直接酸化方法、およびその方法で使�...

Next Patent: 架橋ポリマーマトリックス、ならびにその作製方法および使用方法