Title:
妊娠障害診断マーカーとしての血中mRNA
Document Type and Number:
Japanese Patent JP2006515517
Kind Code:
A
Abstract:
Methods and kits are provided for diagnosing, monitoring, or predicting the conditions of pre-eclampsia, fetal chromosomal aneuploidy, and pre-term labor in a pregnant woman, as well as for detecting pregnancy in a woman, by quantitatively measuring in the maternal blood the amount of one or more mRNA species encoding human chorionic gonadotropin β subunit (hCG-β), human placental lactogen (hPL), human corticotropin releasing hormone (hCRH), KiSS-1 metastasis-suppressor (KISS1), tissue factor pathway inhibitor 2 (TPFI2), placenta-specific 1 (PLAC1), or glyceraldehyde-3-phosphate dehydrogenase (GAPDH), and comparing the amount of the mRNA species with a standard control.
Inventors:
Rho, Yuk-Min Dennis
Inn, Kyon
Tsui, Boyne
Chiu, Wykun Rossa
Inn, Kyon
Tsui, Boyne
Chiu, Wykun Rossa
Application Number:
JP2006500215A
Publication Date:
June 01, 2006
Filing Date:
January 16, 2004
Export Citation:
Assignee:
THE CHINESE UNIVERSITY OF HONG KONG
International Classes:
C12Q1/68; C12N15/09
Domestic Patent References:
| JP2000513210A | 2000-10-10 | |||
| JP2005525124A | 2005-08-25 |
Foreign References:
| WO2002004678A2 | 2002-01-17 |
Attorney, Agent or Firm:
Hironobu Onda
Makoto Onda
Makoto Onda
Previous Patent: 遺伝子改変されたＢｌａｋｅｓｌｅａ属の生物を使用する、カロチノイド...
Next Patent: ６−置換−Δ６−プレグナンの真菌酸化による１９−ノル−１０β−カルボ...
Next Patent: ６−置換−Δ６−プレグナンの真菌酸化による１９−ノル−１０β−カルボ...