Title:
ノルエピネフリン再取り込み阻害活性及び5-HT2Aアンタゴニスト活性を示す化合物を有する、血管運動症状を治療する方法。
Document Type and Number:
Japanese Patent JP2006516023
Kind Code:
A
Abstract:
The present invention relates to the use of compounds and composition of compounds that modulate norepinephrine levels for the treatment of vasomotor symptoms such as thermoregulatory disorders. Furthermore, the present invention relates to the use of compounds and compositions of compounds having norepinephrine reuptake inhibitor (NRI) activity alone or norepinephrine reuptake inhibitor and serotonin reuptake inhibitor (NRI/SRI) dual activity in combination with 5-HT2a receptor antagonist activity.
Inventors:
Dieter, Dahrain, Coleman
Merchen Thaler, Istvan, Joseph
Merchen Thaler, Istvan, Joseph
Application Number:
JP2004545270A
Publication Date:
June 15, 2006
Filing Date:
October 15, 2003
Export Citation:
Assignee:
Wyeth
International Classes:
A61K45/06; A61K31/135; A61K31/335; A61K31/4164; A61K31/445; A61K31/5375; A61K31/55; A61K45/00; A61P9/00; A61P15/08; A61P15/12; A61P43/00
Attorney, Agent or Firm:
Taro Yaguchi
Junichi Omori
Yasuaki Yamaguchi
Junichi Omori
Yasuaki Yamaguchi