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Title:
徐放性治療剤の洞送達
Document Type and Number:
Japanese Patent JP2006520786
Kind Code:
A
Abstract:
The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.

Inventors:
Eaton, Donald Jay.
Moran, Mary El.
Brenneman, Rodney
Application Number:
JP2006507191A
Publication Date:
September 14, 2006
Filing Date:
March 12, 2004
Export Citation:
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Assignee:
Synexus, Inc.
International Classes:
A61K9/00; A61F2/00; A61K47/34; A61L27/40; A61L27/44; A61L27/54; A61L27/58; A61M5/14; A61M31/00; A61F
Domestic Patent References:
JP2001506144A2001-05-15
JP2001520188A2001-10-30
JP2000507630A2000-06-20
JP2003511417A2003-03-25
Foreign References:
WO2001026658A22001-04-19
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita