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Title:
[2-(8,9-ジオキソ-2,6-ジアザビシクロ[5.2.0]ノナ-1(7)-エン-2-イル)アルキル]ホスホン酸の誘導体およびN-メチル-D-アスパルテート(NMDA)受容体アンタゴニストとしてのその使用
Document Type and Number:
Japanese Patent JP2006523694
Kind Code:
A
Abstract:
Compounds of formula (I) or pharmaceutically acceptable salts thereof are provided where at least one of R2 or R3 is not hydrogen. The compounds of the present invention are N-methyl-D-aspartate (NMDA) receptor antagonists and are useful in treating a variety of conditions present in a mammal that benefit from inhibiting the NMDA receptor.

Inventors:
Reinhard Bernhard Baudi
John Anthony Butera
Application Number:
JP2006509747A
Publication Date:
October 19, 2006
Filing Date:
April 07, 2004
Export Citation:
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Assignee:
Wyeth
International Classes:
C07F9/645; A61K31/675; A61K45/00; A61P3/08; A61P3/10; A61P9/10; A61P11/00; A61P21/00; A61P21/02; A61P25/00; A61P25/04; A61P25/06; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P27/06; A61P29/00; A61P29/02; A61P43/00
Domestic Patent References:
JP2007509055A2007-04-12
JP2006522834A2006-10-05
JP2007509055A2007-04-12
JP2006522834A2006-10-05
Attorney, Agent or Firm:
Mitsuo Tanaka
Tadayuki Motoyama
Kenji Tomita