Title:
JNK阻害剤としてのインダゾール誘導体
Document Type and Number:
Japanese Patent JP2006523721
Kind Code:
A
Abstract:
This invention is generally directed to Indazole Derivatives having the following structure: or pharmaceutically acceptable salt thereof, wherein R1, R2 and A are as defined herein. Such compounds have utility in the treatment of a wide range of diseases and disorders that are responsive to JNK inhibition, such as an inflammatory disease or disorder. Thus, methods of treating such diseases and disorders are also disclosed, as are pharmaceutical compositions containing one or more compounds of the above compounds.
Inventors:
Bagwat, Shri Pad, S.
Yoshitaka Sato
Sakata, Stephen, Tee.
Boer, Chris, A.
Ronald Albers
Sapienza, John
Plantevin, Veronique
Chao, Chi
Sahaslavadi, Kiran
Ferri, rachel
Yoshitaka Sato
Sakata, Stephen, Tee.
Boer, Chris, A.
Ronald Albers
Sapienza, John
Plantevin, Veronique
Chao, Chi
Sahaslavadi, Kiran
Ferri, rachel
Application Number:
JP2006513108A
Publication Date:
October 19, 2006
Filing Date:
April 16, 2004
Export Citation:
Assignee:
Signal Pharmaceuticals, LRC
International Classes:
C07D231/56; A61K31/416; A61K31/4196; A61K31/4245; A61K31/427; A61K31/4439; A61K31/454; A61K31/4709; A61K31/496; A61K31/5377; A61K31/55; A61P1/04; A61P3/04; A61P3/10; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P17/02; A61P17/04; A61P17/06; A61P19/00; A61P19/02; A61P19/06; A61P25/00; A61P27/16; A61P29/00; A61P37/02; A61P37/08; A61P43/00; C07D401/04; C07D401/06; C07D401/12; C07D401/14; C07D403/04; C07D403/06; C07D403/12; C07D403/14; C07D405/04; C07D405/12; C07D405/14; C07D409/04; C07D409/12; C07D409/14; C07D413/04; C07D413/14; C07D417/12
Foreign References:
| WO2002010137A2 | 2002-02-07 |
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Ishii Teiji
Satoshi Fujita