Title:
幹細胞動員に有用な医薬の組み合わせ
Document Type and Number:
Japanese Patent JP2007500157
Kind Code:
A
Abstract:
Combined pharmaceutical preparation containing G-CSF and P1GF as the active substances, are useful in the mobilization of blood stem cells in a patient or subject in need thereof.
Inventors:
Gianni, Alessandro Massimo
Carlo-stella, carmelo
Colotta, Francesco
Carlo-stella, carmelo
Colotta, Francesco
Application Number:
JP2006521487A
Publication Date:
January 11, 2007
Filing Date:
July 23, 2004
Export Citation:
Assignee:
Dompe Fa.le.Ma Sochieta per Azioni
International Classes:
A61K38/00; A61K38/18; A61K38/19; A61K38/22; A61P7/00; A61P35/00; A61P35/02; A61P37/00; A61P41/00; A61P43/00
Other References:
JPN6010042987, ＫＡＤＡＲ，Ｊ．Ｇ． ｅｔ ａｌ, "Ｔｅｃｈｎｉｃａｌ ａｎｄ ｓａｆｅｔｙ ａｓｐｅｃｔｓ ｏｆ ｂｌｏｏｄ ａｎｄ ｍａｒｒｏｗ ｔｒａｎｓｐｌａｎｔａｔｉｏｎ ｕｓｉｎｇ Ｇ−ＣＳＦ ｍｏｂｉｌｉｚｅｄ ｆａｍｉｌｙ ｄｏｎｏｒｓ", Ｔｒａｎｓｆｕｓ Ｓｃｉ, 1996, Ｖｏｌ．１７， Ｎｏ．４, ｐ．６１１−８
JPN7010002303, ＤＥ，Ｒ．Ｅ． ｅｔ ａｌ, "Ｅｆｆｅｃｔｓ ｏｆ ｇｒａｎｕｌｏｃｙｔｅ ｃｏｌｏｎｙ−ｓｔｉｍｕｌａｔｉｎｇ ｆａｃｔｏｒ ａｎｄ ｓｔｅｍ ｃｅｌｌ ｆａｃｔｏｒ， ａｌｏｎｅ ａｎｄ ｉｎ ｃｏｍｂｉｎａｔｉｏｎ， ｏｎ", Ｂｌｏｏｄ, 1994, Ｖｏｌ．８３， Ｎｏ．１２, ｐ．３７９５−９
JPN6010042989, ＣＡＲＬＯ−ＳＴＥＬＬＡ，Ｃ． ｅｔ ａｌ, "Ｄｅｆｉｂｒｏｔｉｄｅ ｉｎ ｃｏｍｂｉｎａｔｉｏｎ ｗｉｔｈ ｇｒａｎｕｌｏｃｙｔｅ ｃｏｌｏｎｙ−ｓｔｉｍｕｌａｔｉｎｇ ｆａｃｔｏｒ ｓｉｇｎｉｆｉｃａｎｔｌｙ ｅｎｈａｎｃｅｓ ｔｈｅ ｍｏｂ", Ｃａｎｃｅｒ Ｒｅｓ, 2002, Ｖｏｌ．６２， Ｎｏ．２１, ｐ．６１５２−７
JPN6010042991, ＨＡＴＴＯＲＩ，Ｋ． ｅｔ ａｌ, "Ｐｌａｃｅｎｔａｌ ｇｒｏｗｔｈ ｆａｃｔｏｒ ｒｅｃｏｎｓｔｉｔｕｔｅｓ ｈｅｍａｔｏｐｏｉｅｓｉｓ ｂｙ ｒｅｃｒｕｉｔｉｎｇ ＶＥＧＦＲ１（＋） ｓｔｅｍ ｃｅｌｌｓ ｆｒｏｍ ｂｏｎｅ−ｍａｒ", Ｎａｔ Ｍｅｄ, 2002, Ｖｏｌ．８， Ｎｏ．８, ｐ．８４１−９
JPN6010042993, ＣＡＲＭＥＬＩＥＴ，Ｐ． ｅｔ ａｌ, "Ｓｙｎｅｒｇｉｓｍ ｂｅｔｗｅｅｎ ｖａｓｃｕｌａｒ ｅｎｄｏｔｈｅｌｉａｌ ｇｒｏｗｔｈ ｆａｃｔｏｒ ａｎｄ ｐｌａｃｅｎｔａｌ ｇｒｏｗｔｈ ｆａｃｔｏｒ ｃｏｎｔｒｉｂｕｔｅｓ ｔｏ ａｎｇｉ", Ｎａｔ Ｍｅｄ, 2001, Ｖｏｌ．７， Ｎｏ．５, ｐ．５７５−８３
JPN7010002303, ＤＥ，Ｒ．Ｅ． ｅｔ ａｌ, "Ｅｆｆｅｃｔｓ ｏｆ ｇｒａｎｕｌｏｃｙｔｅ ｃｏｌｏｎｙ−ｓｔｉｍｕｌａｔｉｎｇ ｆａｃｔｏｒ ａｎｄ ｓｔｅｍ ｃｅｌｌ ｆａｃｔｏｒ， ａｌｏｎｅ ａｎｄ ｉｎ ｃｏｍｂｉｎａｔｉｏｎ， ｏｎ", Ｂｌｏｏｄ, 1994, Ｖｏｌ．８３， Ｎｏ．１２, ｐ．３７９５−９
JPN6010042989, ＣＡＲＬＯ−ＳＴＥＬＬＡ，Ｃ． ｅｔ ａｌ, "Ｄｅｆｉｂｒｏｔｉｄｅ ｉｎ ｃｏｍｂｉｎａｔｉｏｎ ｗｉｔｈ ｇｒａｎｕｌｏｃｙｔｅ ｃｏｌｏｎｙ−ｓｔｉｍｕｌａｔｉｎｇ ｆａｃｔｏｒ ｓｉｇｎｉｆｉｃａｎｔｌｙ ｅｎｈａｎｃｅｓ ｔｈｅ ｍｏｂ", Ｃａｎｃｅｒ Ｒｅｓ, 2002, Ｖｏｌ．６２， Ｎｏ．２１, ｐ．６１５２−７
JPN6010042991, ＨＡＴＴＯＲＩ，Ｋ． ｅｔ ａｌ, "Ｐｌａｃｅｎｔａｌ ｇｒｏｗｔｈ ｆａｃｔｏｒ ｒｅｃｏｎｓｔｉｔｕｔｅｓ ｈｅｍａｔｏｐｏｉｅｓｉｓ ｂｙ ｒｅｃｒｕｉｔｉｎｇ ＶＥＧＦＲ１（＋） ｓｔｅｍ ｃｅｌｌｓ ｆｒｏｍ ｂｏｎｅ−ｍａｒ", Ｎａｔ Ｍｅｄ, 2002, Ｖｏｌ．８， Ｎｏ．８, ｐ．８４１−９
JPN6010042993, ＣＡＲＭＥＬＩＥＴ，Ｐ． ｅｔ ａｌ, "Ｓｙｎｅｒｇｉｓｍ ｂｅｔｗｅｅｎ ｖａｓｃｕｌａｒ ｅｎｄｏｔｈｅｌｉａｌ ｇｒｏｗｔｈ ｆａｃｔｏｒ ａｎｄ ｐｌａｃｅｎｔａｌ ｇｒｏｗｔｈ ｆａｃｔｏｒ ｃｏｎｔｒｉｂｕｔｅｓ ｔｏ ａｎｇｉ", Ｎａｔ Ｍｅｄ, 2001, Ｖｏｌ．７， Ｎｏ．５, ｐ．５７５−８３
Attorney, Agent or Firm:
Kazuo Shamoto
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita