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Title:
リセドロネートの結晶構造の制御方法
Document Type and Number:
Japanese Patent JP2007500189
Kind Code:
A
Abstract:
The present invention relates to a process for controlling the crystal form of 3-pyridyl-1-hydroxy-ethylidene-1,1-bisphosphonic acid salt (Risedronate). The process employs a pH adjustment step to induce the proper hydrate form and thereby avoiding inadvertent nucleation of undesired hydrate forms.

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Inventors:
Jane Ellen Godrsky
Application Number:
JP2006521878A
Publication Date:
January 11, 2007
Filing Date:
July 15, 2004
Export Citation:
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Assignee:
THE PROCTER & GAMBLE COMPANY
International Classes:
C07F9/58; A61K31/675
Attorney, Agent or Firm:
Yoshikazu Tani
Kazuo Abe



 
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