Title:
合成ヘパラナーゼ分子及びその使用
Document Type and Number:
Japanese Patent JP2007506416
Kind Code:
A
Abstract:
The present invention relates to synthetically produced, enzymatically active heparanase nucleic acid molecules that are capable of expression in high yield heterologous expression systems, and to polypeptides encoded by said molecules. Also provided herein are methods of expressing mammalian heparanase in heterologous expression systems, wherein high yields of biologically active heparanase are produced compared to prior art methods.
Inventors:
Ram, Armin
Nardetura, Katerina
Palaolo, Michele
Shitwin Cooler, Kristian
Nardetura, Katerina
Palaolo, Michele
Shitwin Cooler, Kristian
Application Number:
JP2006527328A
Publication Date:
March 22, 2007
Filing Date:
September 17, 2004
Export Citation:
Assignee:
ESTACH YOUT DAY LICHIERQUE DAY VIOLOSIA MORE CORRALE PI ANGE ELETS ESET PEAR
International Classes:
C12N15/09; A61P9/00; A61P29/00; A61P35/00; C12N1/19; C12N5/10; C12N9/24; C12N15/56; A61K38/46
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura