Title:
肥満および関連障害の処置のための、選択的メラニン凝集ホルモンレセプターアンタゴニストとしてのアミノベンズイミダゾール
Document Type and Number:
Japanese Patent JP2007507533
Kind Code:
A
Abstract:
The present invention discloses compounds of formula I wherein Ar, Z, m, n, p, R1 and R8 are herein defined, said compounds being novel antagonists for melanin-concentrating hormone (MCH), as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such MCH antagonists as well as methods of using them to treat obesity, metabolic disorders, eating disorders such as hyperphagia, and diabetes.
Inventors:
Sashikumar, Tabarakulam gala.
Burnett, Duein A.
Burnett, Duein A.
Application Number:
JP2006534183A
Publication Date:
March 29, 2007
Filing Date:
September 30, 2004
Export Citation:
Assignee:
Schering Corporation
International Classes:
C07D235/30; A61K31/454; A61K31/496; A61K31/5377; A61K45/00; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P9/12; C07D401/12; C07D403/12
Foreign References:
| WO2003047568A1 | 2003-06-12 | |||
| WO2003059289A2 | 2003-07-24 | |||
| WO2003015769A1 | 2003-02-27 | |||
| WO2003047568A1 | 2003-06-12 | |||
| WO2003059289A2 | 2003-07-24 | |||
| WO2003015769A1 | 2003-02-27 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita