試料中に存在するターゲットまたは対象物を結合/脱離させるためのデバイスおよび方法 - COMPAGNIE GENERALE DES MATIERES NUCLEAIRES

Title:

試料中に存在するターゲットまたは対象物を結合/脱離させるためのデバイスおよび方法

Document Type and Number:

Japanese Patent JP2007509733

Kind Code:

A

Abstract:

A novel device comprises a support having on the surface a coupling zone (Z) functionalizable with a probe (A) capable of bonding with a target (B) to be coupled, a working electrode (WE) and a counter-electrode (CE) located adjacent to (Z), such that a specific electrical current or potential can be applied to (WE) to cause local variation in the pH of (Z) when (Z), (WE) and (CE) are immersed in aqueous solution. Independent claims are included for: (1) an electrochemical microsystem comprising one or more of the devices; (2) a process for coupling a target (B), present in an aqueous sample, to (A) using the claimed device, involving contacting the sample with (Z) (carrying a probe (A) bonding with (B) in pH-dependent manner), then applying an electrical current or potential to WE to modify the pH of the sample on (Z) so that (A) 'recognizes', specifically bonds to and couples (B); and (3) a corresponding coupling/decoupling method, in which an electrical current or potential is applied to (WE) to modify the pH of the sample on (Z) so that (B) is decoupled from (A).

Inventors:

Celine Escofiere
Gilet Marchand
Frederik Levor-Cavalier
Francoise vinette

Application Number:

JP2006530439A

Publication Date:

April 19, 2007

Filing Date:

May 17, 2004

Export Citation:

Click for automatic bibliography generation Help