Title:
炎症の治療に有用なインドール類
Document Type and Number:
Japanese Patent JP2007516203
Kind Code:
A
Abstract:
There is provided a compound of formula (I), wherein X, Y, Z, R<1>, R<2>, R<3>, R<4> and R<5> have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of microsomal prostaglandin E synthase-1 is desired and/or required, and particularly in the treatment of inflammation.
Inventors:
Olofson, Christopher
Sunna, Edgars
Perkman, Benjamin
Ozora, Vita
Katke Vix, Martins
Calvins, Ivers
Charl, Wesley
Sunna, Edgars
Perkman, Benjamin
Ozora, Vita
Katke Vix, Martins
Calvins, Ivers
Charl, Wesley
Application Number:
JP2006518373A
Publication Date:
June 21, 2007
Filing Date:
July 09, 2004
Export Citation:
Assignee:
BIOLIPOX AB
International Classes:
C07D209/42; A61K31/404; A61K31/4439; A61K31/454; A61P1/02; A61P1/04; A61P1/18; A61P3/10; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P15/08; A61P17/00; A61P17/02; A61P17/06; A61P17/08; A61P19/02; A61P19/06; A61P19/08; A61P21/00; A61P25/00; A61P25/06; A61P27/16; A61P29/00; A61P31/04; A61P31/10; A61P31/12; A61P35/00; A61P37/02; A61P37/08; A61P43/00; C07D401/04; C07D401/12; C07D403/04; C07D403/12; C07D405/04; C07D405/14; C07D409/04
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori
Kobayashi Yoshinori