Title:
呼吸器合胞体ウイルス感染の処置のための多環式薬剤
Document Type and Number:
Japanese Patent JP2007516983
Kind Code:
A
Abstract:
Compounds of formula I
salts, and pharmaceutically acceptable derivatives thereof, wherein: A, together with the atoms to which it is attached, represents an optionally substituted phenyl ring; B-C is an optionally substituted link of the formula -CH 2 -(CH 2 ) z -, where z is 1-4; X and Y are independently selected from O, S and NR 6 , where R 6 is independently selected from hydrogen, C 1-6 alkyl, hydroxy and C 1-6 alkoxy; and R 1 and R 2 ;are as defined herein; are described. The compounds are useful as antiviral agents in particular the treatment of infections involving viruses of the Pneumovirinae subfamily.
Inventors:
Bond, Cyrus
Sanford, Benessa Ann
Lambert, John Nicholas
Rim, Chin Yu
Mitchell, Jeffrey, Peter
Doraphane, Alistair George
Nairn, Roland Henry
Sanford, Benessa Ann
Lambert, John Nicholas
Rim, Chin Yu
Mitchell, Jeffrey, Peter
Doraphane, Alistair George
Nairn, Roland Henry
Application Number:
JP2006545846A
Publication Date:
June 28, 2007
Filing Date:
December 24, 2004
Export Citation:
Assignee:
Bio Uta Scientific Management Proprietary Limited
International Classes:
C07D471/14; A61K31/4188; A61K31/4196; A61K31/422; A61K31/424; A61K31/4245; A61K31/427; A61K31/428; A61K31/433; A61K31/4353; A61K31/437; A61K31/4439; A61K31/454; A61K31/4709; A61K31/4725; A61K31/4985; A61K31/506; A61K31/5377; A61K31/55; A61P31/14; C07D487/04; C07D487/14
Domestic Patent References:
| JPH04270284A | 1992-09-25 | |||
| JPH06507388A | 1994-08-25 | |||
| JPH06505017A | 1994-06-09 |
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Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda