Title:
ホスホネート誘導体としてのイノシン一リン酸デヒドロゲナーゼインヒビター
Document Type and Number:
Japanese Patent JP2007520452
Kind Code:
A
Abstract:
Phosphorus substituted mycophenolate derivatives with anti-cancer, anti-viral, anti-inflammatory and anti-tissue/organ transplant rejection properties having use as therapeutics and for other industrial purposes are disclosed. The compositions inhibit tumor growth, viral growth, inflammation, and tissue/organ transplant rejection and/or are useful therapeutically for the treatment or prevention of cancer, viral infection, inflammation and tissue/organ transplant rejection, as well as in assays for the detection of cancer, viral infection, inflammation and tissue/organ transplant rejection.
Inventors:
Cho, Aesop
Kirschberg, Thorsten A.
Watkins, will
Fardis, Maria
Chung, Li S.
Kirschberg, Thorsten A.
Watkins, will
Fardis, Maria
Chung, Li S.
Application Number:
JP2006536844A
Publication Date:
July 26, 2007
Filing Date:
October 25, 2004
Export Citation:
Assignee:
GILEAD SCIENCES INC (US)
International Classes:
C07F9/572; A61K31/662; A61K31/665; A61K31/675; A61K47/48; A61P29/00; A61P31/12; A61P35/00; A61P37/06; C07D307/88; C07F9/576; C07F9/6533; C07F9/655; C07F9/6558
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita