キナーゼ阻害薬の2-アミノチアゾール-5-芳香族カルボキサミド化合物の製造法

Title:

キナーゼ阻害薬の2-アミノチアゾール-5-芳香族カルボキサミド化合物の製造法

Document Type and Number:

Japanese Patent JP2007521340

Kind Code:

A

Abstract:

The invention relates to processes for preparing compounds having the formula (I) and crystalline forms thereof, wherein Ar is aryl or heteroaryl, L is an optional alkylene linker, and R₂, R₃, R₄, and R₅, are as defined in the specification herein, which compounds are useful as kinase inhibitors, in particular, inhibitors of protein tyrosine kinase and p38 kinase.

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Inventors:

Bang-Chi Chen
Robert Dorogini
Jean Rajunes
John Di Dimarco
Michael Galera
Ramakrishnan Chidambaram

Application Number:

JP2006552303A

Publication Date:

August 02, 2007

Filing Date:

February 04, 2005

Export Citation:

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Assignee:

BRISTOL-MYERS SQUIBB COMPANY

International Classes:

C07D417/12; A61K31/506; A61P35/00; C07C235/28; C07C237/42; C07D277/20; C07D277/56; C07D417/14

Domestic Patent References:

JP2002542193A

2002-12-10

Attorney, Agent or Firm:

Kyousei Tamura
Minato Saito
Nagatoshi Shinagawa

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