Title:
ジヒドロテトラベナジン類およびそれらを含有する医薬組成物
Document Type and Number:
Japanese Patent JP2007522193
Kind Code:
A
Abstract:
The invention provides novel isomers of dihydrotetrabenazine, individual enantiomers and mixtures thereof wherein the dihydrotetrabenazine is a 3,11 b-cis-dihydrotetrabenazine. Also provided are methods for the preparation of the novel isomers, pharmaceutical compositions containing them and their use in treating hyperkinetic movement disorders such as Huntington's disease, hemiballismus, senile chorea, tic, tardive dyskinesia and Tourette's syndrome.
Inventors:
Ian, Clark
Robert, turtle
Grant, Johnston
Robert, tridget
Robert, turtle
Grant, Johnston
Robert, tridget
Application Number:
JP2006552683A
Publication Date:
August 09, 2007
Filing Date:
February 11, 2005
Export Citation:
Assignee:
CAMBRIDGE LABORATORIES (IRELAND) LIMITED
International Classes:
C07D455/06; A61K31/4375; A61P25/14; A61P25/24; C07D471/04; C07D491/14
Attorney, Agent or Firm:
Kenji Yoshitake
Yukitaka Nakamura
Konno Akio
Noritaka Yokota
Takeyasu Ito
Yukitaka Nakamura
Konno Akio
Noritaka Yokota
Takeyasu Ito