Title:
CGRP受容体拮抗薬
Document Type and Number:
Japanese Patent JP2007525450
Kind Code:
A
Abstract:
The present invention is directed to compounds of Formula I and Formula II: (where variables R1, R2, R3, R4, R6, A, B, G, J, W, X and Y are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
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Inventors:
Basily, Christopher S
Paone, Daniel Buoy
Anthony Davrilleu
Williams, Teresa M
Paone, Daniel Buoy
Anthony Davrilleu
Williams, Teresa M
Application Number:
JP2006509941A
Publication Date:
September 06, 2007
Filing Date:
April 09, 2004
Export Citation:
Assignee:
MERCK & COMPANY INCOPORATED
International Classes:
C07D401/14; A61K31/4545; A61K31/55; A61K31/551; A61K31/553; A61P25/06; A61P29/00; C07D405/14; C07D413/14; A61K
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Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura